Nouveaux inhibiteurs de l'histone désacétylase basés simultanément sur des 1H-pyrroles trisubstituées et des espaceurs aromatiques et hétéroaromatiques
IKERCHEM, S.L.;UNIVERSIDAD DEL PAIS VASCO-EUSKAL HERRIKO UNIBERTSITATEA
发明人:
申请号:
EP10763676.3
公开号:
EP2483242B1
申请日:
2010.10.01
申请国别(地区):
EP
年份:
2013
代理人:
摘要:
The present invention refers to compounds derived from trisubstituted 1H-pyrrole rings and aromatic rings, which have the following formula (I): as well as to the procedure for their preparation and the use thereof for the treatment of cancer by inhibiting histone deacetylases and the therapeutic use of biological processes related to the mentioned inhibition.