Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as Alzheimers disease, type 2 diabetes and Parkinsons disease
SNOW ALAN D.,Snow Alan D.,NGUYEN BETH P.,Nguyen Beth P.,CASTILLO GERARDO M.,Castillo Gerardo M.,SANDERS VIRGINIA J.,Sanders Virginia J.,LAKE THOMAS P.,Lake Thomas P.,LARSEN LESLEY,Larsen Lesley,LARSEN
申请号:
SI200332351
公开号:
SI2527315T1
申请日:
2003.05.30
申请国别(地区):
SI
年份:
2014
代理人:
摘要:
Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of amyloid diseases, especially A² amyloidosis, such as observed in Alzheimers disease, IAPP amyloidosis, such as observed in type 2 diabetes, and synucleinophathies, such as observed in Parkinsons disease, and the manufacture of medicaments for such treatment.