Compounds, compositions and methods for the treatment of amyloid diseases and synucleinopathies such as Alzheimer's disease, type 2 diabetes and Parkinson's disease
SNOW ALAN, D.,NGUYEN, BETH, P.,CASTILLO, GERARDO, M.,SANDERS, VIRGINIA, J.,LAKE, THOMAS, P.,LARSEN, LESLEY,LARSEN, DAVID S.,WEAVERS, REX T.,LORIMER, STEPHEN D.,COFFEN, DAVID, L. ( DECEASED )
申请号:
DK12166370
公开号:
DK2527315T3
申请日:
2003.05.30
申请国别(地区):
DK
年份:
2014
代理人:
摘要:
Bis- and tris-dihydroxyaryl compounds and their methylenedioxy analogs and pharmaceutically acceptable esters, their synthesis, pharmaceutical compositions containing them, and their use in the treatment of amyloid diseases, especially A² amyloidosis, such as observed in Alzheimer's disease, IAPP amyloidosis, such as observed in type 2 diabetes, and synucleinophathies, such as observed in Parkinson's disease, and the manufacture of medicaments for such treatment.