Guidance systems and associated methods are disclosed. One method comprises: receiving macroscan data prior to an operation； defining a body information model from the macroscan data； positioning a navigation component in the body during the operation； generating microscan data with the navigation component； correlating a location in the macroscan data with a location in the microscan data in the body information model； and/or modifying the body information model by combining an image in the microscan data with an image in the macroscan data.
