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A process for the purification of teicoplanin
专利权人:
LEK PHARMACEUTICALS D.D.
发明人:
ANDRENSEK, SAMO,GRAHEK, ROK,MARKO, TOMAZ
申请号:
DK12784250
公开号:
DK2776453T3
申请日:
2012.11.09
申请国别(地区):
DK
年份:
2016
代理人:
摘要:
The invention provides an inexpensive process for isolation of teicoplanin from a fermentation culture of Actinoplanes teichomyceticus in a grade for pharmaceutical application with substantial removal of colours. Applying optimal combination of cation and anion exchange techniques together with further improved purification affords a unique decoloured teicoplanin material. According to some embodiments, the glycopeptide antibiotic is eluted from the ion exchange column at a pH from 5 to below 9.
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