Carl H. June,Bruce L. Levine,Michael D. Kalos,Yangbing Zhao
申请号：
US14409798
公开号：
US20160235787A1
申请日:
2013.07.12
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention relates to compositions and methods for inducing epitope spreading by administering to a mammal an effective amount of a cell genetically modified to express a chimeric antigen receptor (CAR). The invention also relates to identification of antigens and antibodies involved in the epitope spreading associated with CAR T cells.
