Some embodiments are directed to a portable electronic device for analyzing an analyte. The portable electronic device includes a housing, an adapter detachably coupled to the housing and a processor disposed in the housing. The adapter includes a body defining an opening for receiving a test strip and an interface port disposed within the body. The interface port is configured to read a signal from the test strip. The processor is communicably coupled to the interface port. The processor is configured to determine at least one parameter of the analyte based on the signal received from the interface port.
