The present invention relates to a novel serotonin reuptake inhibitor which also exhibits 5-HT2 C antagonistic action (antidepressive and anxiolytic effects), in particular, 5-HT2 C inverse agonistic action comprising Compound (1) :or a pharmaceutically acceptable salt thereofwherein R1, R2 , R3 and R4 are independently hydrogen or C1-6 alkyl etc.； R5 is C4-7 alkyl or -(CR8R9)r-E； R6, R7, R8 and R9 are independently hydrogen, fluorine or C1-6 alkyl； A is C6-10 aryl or heteroaryl etc.； r is 1, 2, 3 or 4； E is C3-8 cycloalkyl or C6-10 aryl etc.； L is oxygen, sulfur or -NR10 -； n is 1, 2 or 3； R10 is hydrogen or C1-6 alkyl etc.； and X is hydrogen or halogen etc.
