SULZER-MOSSE SARAH,LAMBERTH CLEMENS,CEDERBAUM FREDRIK EMIL MALCOLM
申请号：
NZ61923412
公开号：
NZ619234A
申请日:
2012.06.27
申请国别(地区):
NZ
年份:
2016
代理人:
摘要：
Disclosed are { [3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl} piperidine and piperazine tetralin derivatives and analogues as represented by the general formula I, wherein A is x-C(R10R11)-C(=O)-, x-C(R12R13)-C(=S)-, x-O-C(=O)-, x-O-C(=S)-, x-N(R14)-C(=O)-, x-N(R15)-C(=S)-, x-C(R16R17)-SO2-, or x-N=C(R30)-, in each case x indicates the bond that is connected to R1； T is CR18 or N； Y1, Y2, Y3, and Y4 are independently CR19 or N； Q is O or S； n is 1 or 2； p is 1 or 2, providing that when n is 2, p is 1； R1 is 3,5-bis(difluoromethyl)-1H-pyrazol-1-yl； R2, R3, R4, R5, R6, R7, R10, R11, R12, R13, R16, R17, R18,R19 and R30 each independently are hydrogen, halogen, cyano, alkyl, or haloalkyl； R8, R14 and R15 each independently are hydrogen or alkyl； and R9 is phenyl, benzyl or tetralin-1-yl, each optionally substituted with 1 to 3 substituents independently selected from alkyl, haloalkyl, halogen, cyano, hydroxy and amino； or a salt or a N-oxide thereof. Of particular importance are the three compounds 4-(1-{ [3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl} piperidin-4-yl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)pyridine-2-carboxamide, 4-(4-{ [3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl} piperazin-1-yl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)pyridine-2-carboxamide and 3-(4-{ [3,5-bis(difluoromethyl)-1H-pyrazol-1-yl]acetyl} piperazin-1-yl)-N-(1,2,3,4-tetrahydronaphthalen-1-yl)benzamide. Also disclosed is a fungicidal composition comprising at least one compound as defined above and an agriculturally acceptable carrier, optionally comprising an adjuvant, and optionally comprising at least one additional fungicidally active compound.
