PROBLEM TO BE SOLVED: To provide an antioxidant, a cosmetic, a food and drink composition and a pharmaceutical composition that are each superior in ameliorating and preventing effects and therapeutic effects on various skin troubles such as chapped skin, wrinkles, pigmentation, acne, dermatitis and the like caused by an oxidation reaction and the like triggered by ageing, ultraviolet rays and the like in a daily life and are each stable, inexpensive and highly safe.SOLUTION: The antioxidant comprises fructosyl-citrulline as an effective ingredient. The cosmetic comprises fructosyl-citrulline. The food and drink composition comprises fructosyl-citrulline. The pharmaceutical composition comprises fructosyl-citrulline.