The Board of Trustees of the University of Illinois;Vanquish Oncology, Inc.;The Johns Hopkins University
发明人:
Hergenrother Paul J.,Botham Rachel C.,Fan Timothy M.,Gilbert Mark J.,Handley Michael K.,Joshi Avadhut,Riggins Gregory J.,Tarasow Theodore M.
申请号:
US201615243860
公开号:
US10085978(B2)
申请日:
2016.08.22
申请国别(地区):
美国
年份:
2018
代理人:
Haukaas Fortius PLLC `Haukaas Michael H.
摘要:
The invention provides compositions and methods for the induction of cell death, for example, cancer cell death. Combinations of compounds and related methods of use are disclosed, including the use of compounds in therapy for the treatment of cancer and selective induction of apoptosis in cells. The disclosed drug combinations can have lower neurotoxicity effects than other compounds and combinations of compounds.