PROBLEM TO BE SOLVED: To provide a desmoplakin expression inducer involved in adhesive bonding between cells, to provide a desmoplakin cell membrane localization inducer, and further to provide a cosmetic composition by a desmoplakin expression inducing action or a desmoplakin cell membrane localization inducing action.SOLUTION: The invention provides a desmoplakin expression inducer containing Citrus reticulata extract, or peel or fruit extract of it, or a desmoplakin cell membrane localization inducer, and further a cosmetic composition by a desmoplakin expression inducing action of Citrus reticulata extract, or peel or fruit extract of it, or a desmoplakin cell membrane localization inducing action.COPYRIGHT: (C)2016,JPO&INPIT【課題】細胞間の接着結合に関与するデスモプラキンの発現誘導剤、デスモプラキン細胞膜局在誘導剤、更に、デスモプラキンの発現誘導作用又はデスモプラキン細胞膜局在誘導作用による化粧料組成物の提供。【解決手段】マンダリンオレンジ抽出物又は果皮若しくは果実の抽出物を含有するデスモプラキン発現誘導剤、又はデスモプラキン細胞膜局在誘導剤、更に、マンダリンオレンジ抽出物又は果皮若しくは果実の抽出物のデスモプラキン発現誘導作用、又はデスモプラキン細胞膜局在誘導作用による化粧料組成物。【選択図】なし
