Gordon Keller,Maria Cristina Nostro,Audrey Holtzinger,Farida Sarangi
申请号：
US14397657
公开号：
US20150104430A1
申请日:
2013.04.30
申请国别(地区):
US
年份:
2015
代理人:
摘要：
Methods and compositions for producing NKX6-1+ pancreatic progenitor cells and/or insulin producing cells from an endodermal cell population, the method comprising contacting the endodermal cell population with an EGF component, a Nicotinamide component and/or a Noggin component, optionally a combination of at least one EGF component and at least one nicotinamide component to induce the differentiation of at least one endodermal cell into a NKX6-1+ pancreatic progenitor cell, the combination optionally further comprising at least one Noggin component.
