KELLER, GORDON,NOSTRO, MARIA CRISTINA,HOLTZINGER, AUDREY,SARANGI, FARIDA
申请号：
EP13784648
公开号：
EP2844739A4
申请日:
2013.04.30
申请国别(地区):
EP
年份:
2015
代理人:
摘要：
Methods and compositions for producing NKX6-1+ pancreatic progenitor cells and/or insulin producing cells from an endodermal cell population, the method comprising contacting the endodermal cell population with an EGF component, a Nicotinamide component and/or a Noggin component, optionally a combination of at least one EGF component and at least one nicotinamide component to induce the differentiation of at least one endodermal cell into a NKX6-1+ pancreatic progenitor cell, the combination optionally further comprising at least one Noggin component.
