The disclosed technology relates to chemical entities for the detection of wounds, e.g., chronic wounds or infected wounds, including compositions, substrates, kits, dressing materials, and articles, and systems containing such compounds. The disclosed technology further relates to methods of using these compositions, kits and systems in diagnostic assays, and in the diagnosis and/or detection of chronic or infected wounds based on enzymatic action on specific moieties and/or reaction sites. The disclosed technology additionally relates to detection of pathogenic, e.g., bacterial and/or viral substances, such as enzymes and substrates, at the wound situs. Additional disclosure relates to methods of characterizing wounds based on expression of a plurality of markers and using such information to treat, manage, and follow-up patients suffering from chronic or infected wounds.所公開的技術涉及用於檢測傷口,例如慢性傷口或感染傷口的化學實體,其包含組合物、底物、套組、敷料材料、和製品,並且涉及含有這樣的化合物的系統。所公開的技術進一步涉及基於對特異性部分和/或反應性位點的酶作用在診斷測定中以及在慢性或感染傷口的診斷和/或檢測中使用這些組合物、套組和系統的方法。所公開的技術另外涉及在傷口部位的致病的,例如細菌和/或病毒物質,如酶和底物的檢測。另外的公開內容涉及基於多種標記物的表現來表徵傷口並且使用這樣的資訊治療、控制、隨訪受慢性或感染傷口困擾的患者的方法。
