Jurgen G. Schmidt,Mark Wolfenden,Aaron Anderson,Jennifer Foster Harris,Alexander Koglin
申请号:
US13294963
公开号:
US20120122079A1
申请日:
2011.11.11
申请国别(地区):
US
年份:
2012
代理人:
摘要:
A compound, or a pharmaceutically acceptable salt, ester, hydrate or solvate thereof, comprising formula IV:A-Bwherein A comprises a substrate for an enzyme of a microorganismB comprises an odorant moietyB is covalently bonded to an anomeric carbon of A andA is enzymatically cleavable from B at the covalent bond site between A and B by the enzyme of the microorganism.Examples of such compounds are referred to as substrate-odorant compounds or odorant chimeras.Also disclosed are methods for detecting a microorganism that include contacting the compound with a sample that may include the microorganism.