Damian O Arnaiz,Greg Brown,Emmanuel Claret,Arwed Cleve,David Davey,William Guilford,Seock-Kyu Khim,Thomas Kirkland,Monica J Kochanny,Amy Liang,David Light,John Parkinson,David Vogel,Guo Ping Wei,Bin Y
申请号：
US12771659
公开号：
US08569303B2
申请日:
2010.04.30
申请国别(地区):
US
年份:
2013
代理人:
摘要：
This invention is directed to compounds of formula (I):where r, q, R, R2, R3, R4, R5a, R5b, R5c, R6a, R6b, R6c, R7, R8, and R9 are described herein, as single stereoisomers or as mixtures of stereoisomers, or pharmaceutically acceptable salts, solvates, clathrates, polymorphs, ammonium ions, N-oxides or prodrugs thereof； which are leukotriene A4 hydrolase inhibitors and therefore useful in treating inflammatory disorders. Pharmaceutical compositions comprising the compounds of the invention and methods of preparing the compounds of the invention are also disclosed.
