Damian O. Arnaiz,Greg Brown,Emmanuel Claret,Arwed Cleve,David Davey,William Guilford,Seock-Kyu Khim,Thomas Kirkland,Monica J. Kochanny,Amy Liang,David Light,John Parkinson,Guo Ping Wei,Bin Ye
申请号：
US14313672
公开号：
US09315509B2
申请日:
2014.06.24
申请国别(地区):
US
年份:
2016
代理人:
摘要：
This invention is directed to compounds of formula (I):where r, q, R, R2, R3, R4, R5a, R5b, R5c, R6a, R6b, R6c, R7, R8, and R9 are described herein, as single stereoisomers or as mixtures of stereoisomers, or pharmaceutically acceptable salts, solvates, clathrates, polymorphs, ammonium ions, N-oxides or prodrugs thereof； which are leukotriene A4 hydrolase inhibitors and therefore useful in treating inflammatory disorders. Pharmaceutical compositions comprising the compounds of the invention and methods of preparing the compounds of the invention are also disclosed.
