Joseph H. Gorman, III,Robert C. Gorman,Mahsa Ranji
申请号：
US12935755
公开号：
US08473036B2
申请日:
2009.04.01
申请国别(地区):
US
年份:
2013
代理人:
摘要：
Disclosed herein are devices for assessing mitochondrial function in a living subject comprising a catheter comprising a sheath defining a lumen, a distal end, and a proximal end comprising a light guide for radiating light onto a target within the subject and for receiving a fluorescence signal from the target a light source, wherein the catheter is adapted for transmitting light from the light source to the light guide and, a detector for receiving the fluorescence signal from the light guide and for correlating the fluorescence signal to the mitochondrial function of the target. Also disclosed are methods for assessing mitochondrial function in a living subject comprising placing a catheter proximate to a site of interest within the subject using the catheter to acquire fluorescence signals from cells at the site of interest and, correlating the fluorescence signals to the mitochondrial function of the cells.
