The present invention provides a Saccharomyces cerevisiae strain with a high yield of β-phenylethanol and an application thereof. The Saccharomyces cerevisiae strain with a high yield of β-phenylethanol was collected in the China Center for Type Culture Collection on December 16, 2016, under CCTCC NO: M 2016785. The strain has the ability to provide a high yield of β-phenylethanol and is applied to yellow rice wine fermentation, cooking wine fermentation, vinegar brewing, soy sauce fermentation and liquor fermentation, with β-phenylethanol contents being up to 410 mg/L, 450 mg/L, 300 mg/L, 200 mg/L, 110 mg/L, and 370 mg/L respectively.