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COMPOSITION PHARMACEUTIQUE DE TYPE STRUCTURE UNITAIRE POUR UNE ADMINISTRATION D'ACIDE NUCLÉIQUE
专利权人:
THE UNIVERSITY OF TOKYO;NANOCARRIER CO., LTD.
发明人:
KATAOKA, KAZUNORI,MIYATA, KANJIRO,NISHIYAMA, NOBUHIRO,OSADA, KENSUKE,WATANABE, SUMIYO,FUKUSHIMA, SHIGETO,CHAYA, HIROYUKI,TAKEMOTO, HIROYASU,KATO, YASUKI
申请号:
EP13782198
公开号:
EP2842546A4
申请日:
2013.04.30
申请国别(地区):
EP
年份:
2015
代理人:
摘要:
According to the present invention, it is possible to improve the blood retention capability by a carrier for delivering a nucleic acid such as siRNA. A unit structure-type pharmaceutical composition of the present invention contains a block copolymer having a cationic polyamino acid segment and a hydrophilic polymer chain segment and a nucleic acid; the composition is electrically neutral by counterbalancing negative charge (s) of the nucleic acid with positive charge(s) of the cationic polyamino acid segment, and the nucleic acid is covered with the hydrophilic polymer chain segment.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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