Promoter and viral vector containing the same

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专利权人:

Jin-Hwang Liu

发明人:

Jin-Hwang Liu,Chin-Cheng Liu

申请号：

US12907565

公开号：

US08263398B2

申请日:

2010.10.19

申请国别(地区):

US

年份:

2012

代理人:

摘要：

The invention constructs an activating KRASmutant but not p53-responsive promoter and generates an E1B-55kD-deleted (ΔE1B-55kD) adenovirus, harboring a transcriptionally activating transgene and holding lytic replication ability in the tumor cells with activating KRASmutant. The adenovirus of the invention can be used in the treatment of cancers.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/