HENRIKSEN, Jonas Rosager,ANDRESEN, Thomas Lars,KJÆR, Andreas,RASMUSSEN, Palle Hedengran,PETERSEN, Anncatrine Luisa
申请号：
DK11804942
公开号：
DK2651447T3
申请日:
2011.12.14
申请国别(地区):
DK
年份:
2018
代理人:
摘要：
The present invention is directed to the technical field of imaging compositions useful for diagnosing cancer and other diseases in a subject. In particular, the invention relates to a class of diagnostic compounds comprising a novel liposome composition with encapsulated metal entities such as radionuclides, for example 61Cu and 64Cu copper isotopes. The invention further relates to a novel method for loading delivery systems, such as liposome compositions, with metal entities such as radionuclides, and the use of liposomes for targeted diagnosis and treatment of a target site, such as cancerous tissue and, in general, pathological conditions associated with leaky blood vessels. The present invention provides a new diagnostic tool for the utilization of positron emission tomography (PET) imaging technique.
