Anncatrine Luisa Petersen,Jonas Rosager Henriksen,Palle Hedengran Rasmussen,Andreas Kjær,Thomas Lars Andresen
申请号：
US14968019
公开号：
US20160158392A1
申请日:
2015.12.14
申请国别(地区):
US
年份:
2016
代理人:
摘要：
The present invention is directed to the technical field of imaging compositions useful for diagnosing cancer and other diseases in a subject. In particular, the invention relates to a class of diagnostic compounds comprising a novel liposome composition with encapsulated metal entities such as radionuclides, for example 61Cu and 64Cu copper isotopes. The invention further relates to a novel method for loading delivery systems, such as liposome compositions, with metal entities such as radionuclides, and the use of liposomes for targeted diagnosis and treatment of a target site, such as cancerous tissue and, in general, pathological conditions associated with leaky blood vessels. The present invention provides a new diagnostic tool for the utilization of positron emission tomography (PET) imaging technique.
