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INTRACELLULAR VIRAL VECTOR DELIVERY METHOD EMPLOYING IRON ION/VIRAL VECTOR COMPOSITE
专利权人:
Young Chul Sung
发明人:
Young Chul Sung,Sang Hoon Park,Ki Seok Park
申请号:
US13499101
公开号:
US20120183573A1
申请日:
2010.09.28
申请国别(地区):
US
年份:
2012
代理人:
摘要:
The present invention relates to an intracellular viral vector delivery method employing an iron ion/viral vector composite. The iron ion/viral vector composite according to the present invention is not dependent on the expression of CAR and so improves the efficiency of delivery of viral vectors and gene expression in cells of diverse types, and has an outstanding virus-neutralizing antibody escape performance, exhibits little cytotoxicity and is outstandingly stable even when subjected to iron ion processing at low concentration, and hence can be used to advantage in recombinant viral vaccine compositions.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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