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Fused aminodihydrothiazine derivatives
专利权人:
Ltd.;Eisai R&D Management Co.
发明人:
Adrian Hall,Christopher Neil Farthing
申请号:
US13685109
公开号:
US08592408B2
申请日:
2012.11.26
申请国别(地区):
US
年份:
2013
代理人:
摘要:
The present invention relates to a fused aminodihydrothiazine derivative of formula (I):whereinX is hydrogen or fluorine;A is CH or N;Y is methyl, ethyl, monofluoromethyl, difluoromethyl, trifluoromethyl, difluoroethyl, methoxy, ethoxy, methoxymethyl or —C≡N;and pharmaceutically acceptable salts thereof;which compound has an Aβ production inhibitory effect or a BACE1 inhibitory effect and is useful as a prophylactic or therapeutic agent for a neurodegenerative disease caused by Aβ and typified by Alzheimer-type dementia.
来源网站:
中国工程科技知识中心
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http://www.ckcest.cn/home/

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