The present invention relates to the use of a composition comprising sodium percarbonate in the treatment of skin-related symptoms associated with indications chosen from Acne vulgaris and/or Diabetic Peripheral Neuropathy, wherein the treatment is topical. It further relates to the use of a composition comprising sodium percarbonate for the treatment and prevention of follicular lesions associated with Acne vulgaris, and of lesions associated with Diabetic Peripheral Neuropathy.