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Anticancer agent
专利权人:
Hitomi Yuki;Tetsuo Nagano;Shigeyuki Yokoyama;Hirotatsu Kojima;Keiko Tsuganezawa;Nae Saito;Takayoshi Okabe;Masanao Abe;Hirofumi Nakano;Teruki Honma;Akiko Tanaka
发明人:
Tetsuo Nagano,Takayoshi Okabe,Hirotatsu Kojima,Nae Saito,Hirofumi Nakano,Masanao Abe,Akiko Tanaka,Teruki Honma,Shigeyuki Yokoyama,Keiko Tsuganezawa,Hitomi Yuki
申请号:
US13643002
公开号:
US09156827B2
申请日:
2011.04.28
申请国别(地区):
US
年份:
2015
代理人:
摘要:
An anticancer agent comprising a compound represented by the formula (I) [R1 represents hydrogen atom, hydroxyl group, a C1-6 alkoxy group and the like; R2 and R3 represents hydrogen atom, a halogen atom, a C1-6 alkyl group and the like; R4 represents hydrogen atom, a C1-6 alkyl group, a C1-6 alkylsulfonyl group and the like; R5 represents hydrogen atom or a substituent; represents a single bond or a double bond; R6 and R7 represents hydrogen atom, a C1-6 alkyl group and the like; R8 represents hydrogen atom, a C1-6 alkyl group and the like; A represents —O—, —S—, or —CH2—; D represents —C═ or —N═; X represents methylene group, —O—, or —CO—; Q represents —N═ or —C(R8)═; and Y represents a heterocyclic group or amino group], which shows a superior inhibitory activity against pim-1 kinase.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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