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Antitumor agent effect enhancer
专利权人:
大鵬薬品工業株式会社
发明人:
藤田 英憲,加藤 正徳
申请号:
JP2013551770
公开号:
JP5852678B2
申请日:
2012.12.27
申请国别(地区):
JP
年份:
2016
代理人:
摘要:
An antitumor effect potentiator of another antitumor agent, including an acylthiourea compound represented by formula (I) or a pharmaceutically acceptable salt thereof as an active ingredient: wherein R 1 represents a C 1-6 alkyl group which may have a substituent, while the substituent represents any one of a hydroxyl group, a C 3-10 cycloalkyl group, a C 1-6 alkoxy group which may have a substituent, a C 1-6 alkylamino group which may have a substituent, a C 1-6 alkanoylamino group, a C 1-6 alkylsulfonyl group, a C 6-14 aromatic hydrocarbon group which may have a substituent, a saturated or unsaturated heterocyclic group which may have a substituent, a C 1-6 alkylaminocarbonyl group which may have a substituent, a saturated or unsaturated heterocyclic carbonyl group which may have a substituent; R 2 represents a fluorine atom or a chlorine atom; and R 3 represents a hydrogen atom, a fluorine atom, or a chlorine atom.
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