Kurt Gordon PIKE,Bernard Christophe BARLAAM,Thomas Anthony HUNT,Andrew John EATHERTON
申请号：
US15772120
公开号：
US20180280377A1
申请日:
2016.11.02
申请国别(地区):
US
年份:
2018
代理人:
摘要：
The specification generally relates to compounds of Formula (I):and pharmaceutically acceptable salts thereof, where R1, R2, R3 and R4 have any of the meanings defined herein. The specification also relates to the use of compounds of Formula (I) and salts thereof to treat or prevent ATM mediated disease, including cancer. The specification further relates to pharmaceutical compositions comprising substituted imidazo[4,5-c]quinolin-2-one compounds and pharmaceutically acceptable salts thereof； kits comprising such compounds and salts； methods of manufacture of such compounds and salts； and intermediates useful in such manufacture.
