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IMIDAZO[4,5-C] QUINOLIN -2-ONE COMPOUNDS AND THEIR USE IN TREATING CANCER
专利权人:
ASTRAZENECA AB
发明人:
PIKE, Kurt, Gordon,BARLAAM, Bernard, Christophe,HUNT, Thomas, Anthony,EATHERTON, Andrew, John
申请号:
PH12018500958
公开号:
PH12018500958A1
申请日:
2018.05.03
申请国别(地区):
PH
年份:
2018
代理人:
摘要:
The specification generally relates to compounds of Formula (I) and pharmaceutically acceptable salts thereof, where x, R1, R2, R3, R4 and R5 have any of the meanings defined herein. The specification also relates to the use of compounds of Formula (I) and salts thereof to treat or prevent ATM mediated disease, including cancer. The specification further relates to pharmaceutical compositions comprising substituted imidazo[4,5-c]quinolin-2-one compounds and pharmaceutically acceptable salts thereof; kits comprising such compounds and salts; methods of manufacture of such compounds and salts; and intermediates useful in such manufacture.
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中国工程科技知识中心
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http://www.ckcest.cn/home/

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