The present invention provides a kind of compositions of whitening wortmannin, contain as active constituent. The composition of whitening wortmannin, it contains the skin-whitening as active constituent, according to the present invention, by the generation for reducing melanin, inhibit the activation of tyrosinase expression, and reduce the relevant gene of melanogenesis and albumen, can be widely applied to skin appearance, cosmetic composition and pharmaceutical composition, by not having dysgenic cell with stability.The 2014 of copyright KIPO submissions
