Thomas F. Miller, III,William M. Clemons, Jr.,Stephen Marshall,Axel Mueller,Michiel Niesen,Bin Zhang
申请号:
US14301070
公开号:
US10013525B1
申请日:
2014.06.10
申请国别(地区):
US
年份:
2018
代理人:
摘要:
Methods and systems are described to provide computerized trajectory-based methods to represent translocon-associated protein trajectories, provide proteins or protein sequences with desired translocon-associated biogenesis features, screening proteins or protein sequences to provide proteins or protein sequences with desired translocon-associated biogenesis features, screening translocon-associated biogenesis feature determinants to provide proteins or protein sequences with desired translocon-associated biogenesis features, identifying translocon-associated biogenesis feature determinants of a given protein sequence, computer-based protein sequence identification methods, computer-based methods for identifying correlations in a set of protein sequences, computer-based methods for identifying correlations between experimental data and computer-generated data in a protein sequence, and computer-based methods for determining which modifications of a protein sequence do not substantially affect a translocon-associated biogenesis feature of the protein sequence.