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USE OF 1,2-DICARBOXYLIC ACID MONOAMIDE POLYMER AS SYNERGIST FOR CHEMOTHERAPY
专利权人:
发明人:
Husheng YAN,Jun CAO
申请号:
US15987005
公开号:
US20180339053A1
申请日:
2018.05.23
申请国别(地区):
US
年份:
2018
代理人:
摘要:
A use of a polymer as a synergist for a chemotherapeutic drug, wherein the polymer is a polymer having a 1,2-dicarboxylic acid monoamide structure, and after the polymer, a chemotherapeutic drug and a cancer cell are co-incubated in a slightly acidic environment which simulates a tumor tissue, a survival rate of the cancer cell is lower than that of a cancer cell incubated under the same conditions without the polymer. The polymer and the chemotherapeutic drug are injected together into a tumor-bearing animal body, the tumor-growth inhibiting effect thereof is better than that with injection of the same dosage of the chemotherapeutic drug alone.
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