PROBLEM TO BE SOLVED: To provide hepatic protection agent improved in digestive and absorption efficiency, and to provide application thereof.SOLUTION: A hepatoprotective agent contains eggshell membrane-containing fine powder, wherein the eggshell membrane-containing fine powder is eggshell membrane-containing fine powder having a volume mean particle diameter of 6 &mu；m or less and/or eggshell membrane-containing fine powder having a volume maximum particle diameter of 20 &mu；m or less. When fed with feed including eggshell membrane-containing fine powder with these values (sample C), the liver injury group (CCl) has caused a significant weight loss compared with the control group (control), whereas an eggshell membrane-fed group (ESM) has maintained the equal weight to the control group.【課題】消化吸収効率の改善された肝保護剤およびその応用を提供すること。【解決手段】この肝保護剤は、卵殻膜含有微粉末を有し、その卵殻膜含有微粉末は、体積平均粒子径が６μｍ以下の卵殻膜含有微粉末および／または体積最大粒子径が２０μｍ以下の卵殻膜含有微粉末となっている。この値の卵殻膜含有微粉末（サンプルＣ）を含む飼料を与えた場合、試験群ＥＳＭは、対照群（ｃｏｎｔｒｏｌ）と比較して肝障害群（ＣＣｌ４）は有意に体重低下を起こしたのに対し、卵殻膜摂取群（ＥＳＭ）は対照群と同等の体重を維持した。【選択図】図１
