Donald R. Owen,David C. Kravitz,John Brassil,Kelvin G. M. Brockbank,Andrew Burroughs,Douglas Schein,Stanley Harris,Dennis Steibel,Richard Fraser,Dickon Isaacs
申请号：
US13137383
公开号：
US08445260B2
申请日:
2011.08.10
申请国别(地区):
US
年份:
2013
代理人:
摘要：
An organ perfusion apparatus and method monitor, sustain and/or restore viability of organs and preserve organs for storage and/or transport. Other apparatus include an organ transporter, an organ cassette and an organ diagnostic device. In perfusion, organ perfusion pressure is preferably controlled in response to a sensor disposed in an end of tubing placed in the organ, by a pneumatically pressurized medical fluid reservoir, providing perfusion pressure fine tuning, overpressurization prevention and emergency flow cut-off. In the hypothermic mode, the organ is perfused with a medical fluid, preferably a simple crystalloid solution containing antioxidants, intermittently or in slow continuous flow. The medical fluid may be fed into the organ from an intermediary tank having a low pressure head to avoid organ overpressurization. Viability of the organ may be automatically monitored, preferably by monitoring characteristics of the medical fluid perfusate. The perfusion process can be automatically controlled using a control program.
