BAR, LILIANA,BELYAEV, OLEG,MEIDLER, ROBERTO,MINTZ, RONI,NUR, ISRAEL
申请号：
CA3064119
公开号：
CA3064119A1
申请日:
2012.05.14
申请国别(地区):
CA
年份:
2012
代理人:
摘要：
The invention relates to an immunoglobulin composition reduced in thrombogenicagents and tomethods for its preparation. One method comprises subjecting an immunoglobulincontainingsolution to a negative cation exchanger chromatography at a pH in the range ofhigher than 3.8to equal to or lower than 5.3. The solution can also be subjected to anegative anion exchangerchromatography at a pH in the range of 7 to 8.2.
