Immunoglobulin reduced in thrombogenic agents and preparation thereof

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专利权人:

Omrix Biopharmaceuticals Ltd.

发明人:

Roni Mintz,Oleg Belyaev,Israel Nur,Liliana Bar,Roberto Meidler

申请号：

US14678319

公开号：

US09796770B2

申请日:

2015.04.03

申请国别(地区):

US

年份:

2017

代理人:

摘要：

The invention relates to an immunoglobulin composition reduced in thrombogenic agents and to methods for its preparation. One method comprises subjecting an immunoglobulin containing solution to a negative cation exchanger chromatography at a pH in the range of higher than 3.8 to equal to or lower than 5.3. The solution can also be subjected to a negative anion exchanger chromatography at a pH in the range of 7 to 8.2.

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