PROBLEM TO BE SOLVED: To provide a preparation having high skin-whitening effect.SOLUTION: The present invention provides a skin external preparation for inhibiting melanogenesis comprising a compound represented by general formula (I) or a salt thereof, and a phenol having tyrosinase inhibitory activity. (In the formula, where n represents an integer of 0-2, m represents 1 or 2, R represents a hydrophilic group obtained by removing one hydroxy group from glycerol, and a broken line in the formula represents a single bond or double bond).SELECTED DRAWING: Figure 7COPYRIGHT: (C)2016,JPO&INPIT【課題】高い美白効果を有する製剤の提供。【解決手段】下記一般式(I)で表される化合物又はその塩と、チロシナーゼ阻害活性を有するフェノール類とを含む、メラニン産生抑制用の皮膚外用剤。(式中、nは0~2の整数を表し、mは1又は2を表し、Rはグリセロールから1つの水酸基が除かれた親水性基を表し、は一重結合又は二重結合を表す。)【選択図】図7
