A physiological detection device includes one or more first detection electrode groups, one or more second detection electrode groups and a microprocessor.The first detection electrode group comprises a first electrode and a relative second electrode.The second detection electrode group comprises a third electrode and a relative fourth electrode.The first electrode contacts the hand of the subject, the second electrode contacts the acupoint and its block of the subject, so that the microprocessor transmits the electric wave signal through the first electrode, and receives the reverse electric wave signal through the second electrode to convert the first detection value.The third electrode and the fourth electrode are respectively contacted around the acupoint of the subject, so that the microprocessor can detect the change of capacitance and convert the first and second detection values.The microprocessor analyzes the first detection value and the second detection value to get the first detection result.一種生理檢測裝置包括一或多個第一檢測電極組、一或多個第二檢測電極組及一微處理器。第一檢測電極組包含一第一電極以及一相對的第二電極。第二檢測電極組包含一第三電極以及一相對的第四電極。第一電極接觸受測者的手部，第二電極接觸受測者的穴位及其區塊，使微處理器透過第一電極發射電波信號，並透過第二電極接收反請的電波信號而換算出一第一檢測值。第三電極及第四電極分別接觸受測者的穴位周圍處，使微處理器檢測電容變化而換算出一第二檢測值。微處理器對第一檢測值及第二檢測值進行分析得到一檢測結果。
