The present invention relates to an apparatus and a method for targeted drug delivery by use of a drug substance comprising a drug and magnetic particles. The apparatus comprises selection means for generating a magnetic selection field (50) having a pattern in space of its magnetic field strength such that a first sub-zone (52) having a low magnetic field strength where the magnetization of the magnetic particles is not saturated and a second sub- zone having a higher magnetic field strength where the magnetization of the magnetic particles is saturated are formed in a field of view (28), drive means for changing the position in space of the two sub-zones (52, 54) in the field of view (28) by means of a magnetic drive field so that the magnetization of the magnetic particles changes locally, and a control unit (150) for controlling said drive means to change the position in space of the two sub-zones (52, 54) such that after administration of the drug substance the first sub-zone (52) is moved through a surrounding area (320) arranged around a target area (310) except through the target area (310) itself, said surrounding area (320) representing a potentially affected volume and/or having a predetermined maximal distance from said target area (310).La présente invention concerne un appareil et un procédé pour ladministration ciblée de médicament à laide dune substance de médicament comprenant un médicament et des particules magnétiques. Lappareil comprend des moyens de sélection pour générer un champ de sélection magnétique (50) comprenant un motif dans lespace de son intensité de champ magnétique de telle sorte quune première zone secondaire (52) ayant une faible intensité de champ magnétique, la magnétisation des particules magnétiques nétant pas saturée, et une seconde zone secondaire ayant une plus grande intensité de champ magnétique, la magnétisation des particules magnétiques étant saturée, sont formées dans un champ de vision (28), des moyens dentraînement
