PROCÉDÉS POUR LA SYNTHÈSE DE KOTALANOL ET DE STÉRÉO-ISOMÈRES ET ANALOGUES DE CELUI-CI ET NOUVEAUX COMPOSÉS PRODUITS PAR LES PROCÉDÉS

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专利权人:

SIMON FRASER UNIVERSITY

发明人:

PINTO, BRIAN, MARIO,KUMARASAMY, JAYAKANTHAN,NASI, RAVINDRANATH,MOHAN, SANKAR

申请号：

EP09724047

公开号：

EP2274293A4

申请日:

2009.03.25

申请国别(地区):

EP

年份:

2012

代理人:

摘要：

Compounds having the general formula (I): wherein X is S, Se or NH, and stereoisomers thereof, and de-O-sulfonated analogues of all of the foregoing, but excluding naturally occurring kotalanol and de-O-sulfonated kotalanol, and methods for synthesizing same. The compounds are useful as glycosidase inhibitors, and may be used in the treatment of diabetes. The synthetic compounds may also be used as standards in the calibration or grading of natural or herbal remedies produced from natural sources of glycosidase inhibitors such as kotalanol.

来源网站：

中国工程科技知识中心

来源网址：

http://www.ckcest.cn/home/