Brian BUSSER,Philippe DUCHATEAU,Alexandre JUILLERAT,Laurent POIROT,Julien VALTON
申请号：
US16340222
公开号：
US20200224163A1
申请日:
2017.10.19
申请国别(地区):
US
年份:
2020
代理人:
摘要：
The invention pertains to the field of adaptive cell immunotherapy. It provides with the genetic insertion of exogenous coding sequence(s) that help the immune cells to direct their immune response against infected or malignant cells. These exogenous coding sequences are more particularly inserted under the transcriptional control of endogenous gene promoters that are sensitive to immune cells activation. Such method allows the production of safer immune primary cells of higher therapeutic potential.
