STANISLAV JARACZ,GUOFENG XU,STEVEN MILLER,LEONORA LEIGH,GUILLAUME PICQUET,LAURENCE DU-THUMM
申请号：
ARP120104891
公开号：
AR089390A1
申请日:
2012.12.20
申请国别(地区):
AR
年份:
2014
代理人:
摘要：
Compositions for topical use as bactericide comprising an effective concentration of a compound or galamida gallate, a cycloalkyl or heterocicloalquilo polisustituido, where the substituents are selected from the group consisting of hydroxyl, Hydroxymethyl, Fluorine, Chlorine, Ami No, Nitro, or a group of Formula - X - (CO) - (3,4,5 - trihidroxifenilo)Where X is selected from o and NH, on condition that the substituents comprising at least two groups of Formula - X - (CO) - (3,4,5 - trihidroxifenilo) together with adjacent carbons in free or Salt form acceptable for oral or topical Application, as well as methods to develop and u The same SAR.Claim 6: Composition of claims 1 to 5, wherein the compound is selected from galamida gallate or trans - 1.2 - ciclohexanediol digalato (thdg), cis - (1,2 - ciclohexanediol digalato chdg), cis - 1.2 - ciclopentanediol digalato (CPDG), trans - 1.2 - cyclohexane digalamida (thdga) and CIS - 1.2 - cyclohexane digalamida (chdga) and mixtures thereof.Claim 7: the composition of claim 6, wherein the compound is selected from galamida gallate or trans - 1.2 - ciclohexanediol digalato (thdg), cis - (1,2 - ciclohexanediol digalato chdg) and mixtures thereof.Claim: the composition of any preceding claim, characterized in that it is in the form of a Cream Cleanser or soap, Ointment, antimicrobial for topical application on the skin.Claim 12: Composition of claim 11, wherein is a Toothpaste or Mouthwash that also includes one or more of water, an Abrasive, a Surfactant, a foaming agent, a Vitamin, a Polymer, an enzyme, a Wetting Agent, a Thickener, a antimi Crobiano, a Preservative, FLAVORING, Coloring and / or combinations thereof.Claim: the composition of 14 claims 11 to 13, which is a composition for Oral Care, characterized in that it comprises an effective amount of an additional Agent selected from the group consisting of a source of fluoride ion, arginine in free or Salt form Acceptable for oral Application, an antibacterial agent
