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A PROCESS FOR THE PREPARATION OF PYRVINIUM PAMOATE AND CRYSTALLINE FORMS THEREOF
专利权人:
URQUIMA; S.A
发明人:
DEL RIO PERICACHO, Jose Luis,MARTI VIA, Josep,CANOVAS PAREDES, Antonio de Padua
申请号:
ES201700479
公开号:
ES2689371A8
申请日:
2017.03.29
申请国别(地区):
ES
年份:
2018
代理人:
摘要:
The present invention relates to a process for the preparation of pyrvinium pamoate, which comprises reacting pyrvinium methyl sulphate salt of formula (II) with disodium pamoate of formula (III), in the presence of a base to processes for the preparation of crystalline Form A and crystalline Form III of pyrvinium pamoate as well as a process for the purification of crystalline Form III. It also relates to crystalline Forms A and III of pyrvinium pamoate and to pharmaceutical compositions containing them.
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