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A PROCESS FOR THE PREPARATION OF PYRVINIUM PAMOATE AND CRYSTALLINE FORMS THEREOF
专利权人:
发明人:
申请号:
EP16382169.7
公开号:
EP3231796A1
申请日:
2016.04.13
申请国别(地区):
EP
年份:
2017
代理人:
摘要:
The present invention relates to a process for the preparation of pyrvinium pamoate, which comprises reacting pyrvinium methyl sulphate salt of formula (II) with disodium pamoate of formula (III), in the presence of a base to processes for the preparation of crystalline Form A and crystalline Form III of pyrvinium pamoate as well as a process for the purification of crystalline Form III. It also relates to crystalline Forms A and III of pyrvinium pamoate and to pharmaceutical compositions containing them.
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