LE TIEU BINH,RAMOS ANTONIO D,JOHN STANLY,SMRCINA MARTIN,ROSSE GERARD,PEDGRIFT BRIAN,THORPE DAVID S,CLEMENS JENNIFER,FREED BRIAN S,WIRE WILLIAM,ZHAO JIANHONG,FRANCIS ROBERT S,CAULFIELD THOMAS J
申请号:
IN7158/CHENP/2009
公开号:
IN2009CN07158A
申请日:
2009.12.04
申请国别(地区):
IN
年份:
2015
代理人:
摘要:
The present invention relates to novel compounds of the formula I: wherein in any of its stereoisomeric forms or a mixture of stereoisomeric forms in any ratio, or a physiologically acceptable salt thereof, wherein the substituents are as described herein. The inventive compounds have CXCR5 inhibitory activity are particularly useful in treating or preventing various inflammatory diseases, such as rheumatoid arthritis, multiple sclerosis, lupus, Crohn"s Disease, associated with the modulation of the human CXCR5 receptor.