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Biodegradable particle, vascular embolization material, and method for producing biodegradable particle
专利权人:
東レ株式会社
发明人:
藤田 雅規,中西 恵,高橋 佳丈,山村 泰史,棚橋 一裕
申请号:
JP2012516414
公开号:
JP6094219B2
申请日:
2012.03.29
申请国别(地区):
JP
年份:
2017
代理人:
摘要:
The present invention aims to provide a biodegradable vascular embolization material that is less likely to coagulate and has an improved flexibility, and whose particle shape is recovered after its passing through a catheter or the like. The present invention provides a biodegradable particle comprising a block copolymer produced by copolymerization of: a biodegradable copolymer having a structure composed of hydroxycarboxylic acid a1, whose homopolymer produced by homopolymerization has a glass transition point of not less than 40°C, and hydroxycarboxylic acid a2, whose homopolymer produced by homopolymerization has a glass transition point of not more than -40°C; a water-soluble polymer comprising a functional group selected from the group consisting of a hydroxyl group, amino group and carboxylic acid group at each of both ends; and a polyvalent compound comprising 2 or more functional groups each selected from the group consisting of a hydroxyl group, amino group and carboxylic acid group; wherein the ratio of the mass of the structure composed of hydroxycarboxylic acid a2 to the mass of the biodegradable copolymer is 30 to 90% by mass.
来源网站:
中国工程科技知识中心
来源网址:
http://www.ckcest.cn/home/

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