PROBLEM TO BE SOLVED: To provide a composition that improves immunocompetence.SOLUTION: The present invention provides an immune promoter, an NO production promoter and an IL-12 production promoter comprising basidiomycetous mycelial medium extract, fucoidan, lactic acid bacteria and Houttuyniae.SELECTED DRAWING: NoneCOPYRIGHT: (C)2016,JPO&INPIT【課題】免疫力を改善する組成物を提供する。【解決手段】担子菌菌糸体培養液抽出物、フコイダン、乳酸菌及びバンランコンを含む免疫促進剤、NO産生促進剤及びIL-12産生促進剤を提供する。【選択図】なし