The present invention relates to new compounds of general formula (I) that show great affinity and activity towards the subunit α2δ of voltage-gated calcium channels (VGCC), especially α2δ-1 subunit of voltage-gated calcium channels or dual activity towards subunit α2δ of voltage-gated calcium channels (VGCC), especially α2δ-1 subunit of voltage-gated calcium channels, and noradrenaline transporter (NET). The invention is also related to the process for the preparation of said compounds as well as to compositions comprising them, and to their use as medicaments.本發明是係關於通式(I)之新化合物，該等化合物對電位門控型鈣通道(VGCC)之α2δ次單元、尤其電位門控型鈣通道之α2δ-1次單元顯示出極大的親和性及活性或對電位門控型鈣通道(VGCC)之α2δ次單元、尤其電位門控型鈣通道之α2δ-1次單元與正腎上腺素運輸蛋白(NET)顯示出雙重活性。本發明亦係關於用於製備該等化合物之方法以及包含該等化合物之組成物、以及其作為藥物之用途。
